Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682810 | 1.00 | KDM4E (0.46) | KDM4EPOLBCNR1ALOX5CYP19A1 | |
| SCHEMBL6681781 | 1.00 | KDM4E (0.46) | KDM4EPOLBCNR1ALOX5CYP19A1 | |
| SCHEMBL6682377 | 0.73 | PTGS2 (0.50) | KDM4ECNR1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7276190 | 0.72 | KDM4E (0.56) | KDM4ECNR1CYP19A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8983663 | 0.72 | KDM4E (0.59) | KDM4EPOLBCNR1ALDH1A1MEN1 | |
| SCHEMBL4231056 | 0.71 | EGFR (0.46) | CNR1CYP19A1ALDH1A1SMN1; SMN2PTGS2 | |
| SCHEMBL4219487 | 0.70 | MAPT (0.53) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4430853 | 0.70 | ALDH1A1 (0.60) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL4233003 | 0.67 | MAPT (0.50) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29386220 | 0.67 | ALDH1A1 (0.57) | KDM4EPOLBCNR1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474390-A1 | INDOLE DERIVATIVES SUBSTITUTED WITH LONG-CHAIN ALCOHOLS AND MEDICAMENTS CONTAINING THEM | Meiji Dairies Corporation (JP) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068741-A1 | INDOLE DERIVATIVES SUBSTITUTED WITH LONG-CHAIN ALCOHOLS AND MEDICAMENTS CONTAINING THEM | MEIJI DAIRIES CORPORATION (JP) | 2003-08-21 | — | — | WO | disclosed |