Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 19/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5-Iodo,5'-Deoxytubercidin SCHEMBL6236636 | 0.74 | ADK (1.00) | ADK | |
| 5-Iodo,5'-Deoxytubercidin SCHEMBL8331903 | 0.74 | ADK (1.00) | ADK | |
| SCHEMBL3827614 | 0.72 | ADK (0.57) | ADKADORA3 | |
| SCHEMBL3819268 | 0.72 | ADK (0.57) | ADKADORA3 | |
| SCHEMBL21413874 | 0.70 | ADK (0.44) | ADKADORA3 | |
| SCHEMBL8321626 | 0.70 | ADK (0.76) | ADK | |
| SCHEMBL8323046 | 0.70 | ADK (0.69) | ADK | |
| SCHEMBL1738203 | 0.69 | CYP2C19 (0.45) | ADKADORA3 | |
| SCHEMBL8330319 | 0.69 | ADK (1.00) | ADK | |
| SCHEMBL6678245 | 0.69 | ADK (1.00) | ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832092-B1 | ORALLY ACTIVE ADENOSINE KINASE INHIBITORS | METABASIS THERAPEUTICS INC (US) | 2004-11-17 | — | — | EP | disclosed |
| EP-0832092-A1 | ORALLY ACTIVE ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040706-A1 | ORALLY ACTIVE ADENOSINE KINASE INHIBITORS | GENSIA-SICOR (US) | 1996-12-19 | — | — | WO | disclosed |