Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3898503 | 0.97 | HTR6 (0.32) | HTR2AHTR6 | |
| SCHEMBL17386884 | 0.73 | HTR2A (0.34) | HTR2AHTR6 | |
| SCHEMBL8157271 | 0.73 | HTR2A (0.34) | HTR2AHTR6 | |
| Bromide SCHEMBL8161509 | 0.72 | HTR2A (0.35) | HTR2AHTR6 | |
| SCHEMBL8149561 | 0.71 | HTR6 (0.33) | HTR2AHTR6 | |
| SCHEMBL8163025 | 0.70 | HTR6 (0.33) | HTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL4002087 | 0.69 | HTR6 (0.32) | HTR2AHTR6 | |
| SCHEMBL7164209 | 0.69 | GAA (0.34) | HTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL7781251 | 0.69 | HTR6 (0.32) | HTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL7822194 | 0.68 | HTR6 (0.33) | HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787616-B2 | HIGH BULK DENSITY, NARROW PARTICLE SIZE AND MOLECULAR WEIGHT DISTRIBUTION, REDUCED FINES AND LARGE PARTICLE CONTENT; HIGH ACTIVITY | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| US-20040010104-A1 | Catalyst for olefin polymerization and process for polymerizing olefin by means thereof | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2004-01-15 | — | — | US | disclosed |
| EP-1380598-A1 | Supported catalyst for olefin polymerization and process for polymerizing olefin by means thereof | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2004-01-14 | — | — | EP | disclosed |
| EP-0442725-B2 | Olefin polymerization solid catalysts and process for the polymerization of olefins | MITSUI CHEMICALS INC (JP) | 2003-10-22 | — | — | EP | disclosed |
| EP-0733653-B1 | Method for the preparation of ethylene polymer compositions | MITSUI CHEMICALS INC (JP) | 1998-11-11 | — | — | EP | disclosed |
| EP-0656373-B1 | Olefin polymerization catalyst and process for the polymerization of olefins | MITSUI CHEMICALS INC (JP) | 1998-07-29 | — | — | EP | disclosed |
| US-5605969-A | USING A CATALYST COMPOSED OF A TRANSITION METAL COMPOUND CONTAINING A LIGAND HAVING A CYCLOALKADIENYL SKELETON AND AN ORGANOALUMINUM OXY-COMPOUND; TWO STAGE PROCESS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
| EP-0447035-B1 | Method for the preparation of ethylene polymer compositions | MITSUI PETROCHEMICAL IND (JP) | 1997-01-02 | — | — | EP | disclosed |
| EP-0439964-B1 | Olefin polymerization catalyst and process for the polymerization of olefins | MITSUI PETROCHEMICAL IND (JP) | 1996-10-23 | — | — | EP | disclosed |
| EP-0733653-A2 | Method for the preparation of ethylene polymer compositions | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |
| US-5145818-A | OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR THE POLYMERIZATION OF OLEFINS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-08 | — | — | US | disclosed |
| US-5120696-A | OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR THE POLYMERIZATION OF OLEFINS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-06-09 | — | — | US | disclosed |
| US-5091352-A | An organoalulminum oxy-compound prepared by treating an alumoxane with water or an alcohol; benzene insolubility | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0447035-A2 | Method for the preparation of ethylene polymer compositions | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-09-18 | — | — | EP | disclosed |
| EP-0442725-A2 | Olefin polymerization solid catalysts and process for the polymerization of olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| EP-0439964-A2 | Olefin polymerization catalyst and process for the polymerization of olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |
| EP-0436399-A2 | Olefin polymerization catalyst and process for the polymerization of olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-07-10 | — | — | EP | disclosed |
| US-4990640-A | Polymerization catalyst for alpha-olefin hydrocarbon | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0363029-A2 | Olefin polymerization catalyst component, olefin polymerization catalyst and process for the polymerization of olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-11 | — | — | EP | disclosed |
| EP-0360492-A2 | Benzene-insoluble organo-aluminum oxy-compounds and process for preparing same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-03-28 | — | — | EP | disclosed |