Hydrochloric Acid

Hydrochloric Acid

SCHEMBL3898503

C1=CC(C2(C3C=Cc4ccccc43)CC[Zr+]2)c2ccccc21.[Cl-]

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.32
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL6682824 0.97 HTR2A (0.35) HTR6HTR2A
SCHEMBL8157271 0.73 HTR2A (0.34) HTR6HTR2A
SCHEMBL17386884 0.73 HTR2A (0.34) HTR6HTR2A
Hydrochloric Acid SCHEMBL7781251 0.72 HTR6 (0.32) HTR6HTR2A
Hydrochloric Acid SCHEMBL4002087 0.72 HTR6 (0.32) HTR6HTR2A
SCHEMBL8149561 0.71 HTR6 (0.33) HTR6HTR2A
Hydrochloric Acid SCHEMBL7822194 0.71 HTR6 (0.33) HTR6HTR2A
SCHEMBL8163025 0.70 HTR6 (0.33) HTR6HTR2A
Bromide SCHEMBL8161509 0.69 HTR2A (0.35) HTR6HTR2A
SCHEMBL7164209 0.69 GAA (0.34) HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1461150-A4 BIMETALLIC CATALYSTS WITH HIGHER ACTIVITY UNIVATION TECH LLC (US) 2009-01-28 EP disclosed
US-7160949-B2 Olefin block copolymers, processes for producing the same and uses thereof MITSUI CHEMICALS, INC. (JP) 2007-01-09 US disclosed
US-6995109-B2 Method of making a bimetallic catalyst with higher activity UNIVATION TECHNOLOGIES, LLC (US) 2006-02-07 US disclosed
EP-1275670-B1 OLEFIN BLOCK COPOLYMERS, PRODUCTION PROCESSES OF THE SAME AND USE THEREOF MITSUI CHEMICALS INC (JP) 2005-08-10 EP disclosed
EP-1546210-A1 REACTOR WALL COATING AND PROCESSES FOR FORMING SAME Univation Technologies, LLC (US) 2005-06-29 EP disclosed
US-6870023-B2 Reactor wall coating and processes EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-03-22 US disclosed
US-6855654-B2 Bimetallic catalyst for ethylene polymerization reactions with uniform component distribution EXXONMOBIL OIL CORPORATION (US) 2005-02-15 US disclosed
US-20050003950-A1 Method of making mixed ziegler-natta/metallocece catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2005-01-06 US disclosed
US-20040198588-A1 Bimetallic catalysts with higher activity UNIVATION TECHNOLOGIES, LLC 2004-10-07 US disclosed
EP-1461150-A1 BIMETALLIC CATALYSTS WITH HIGHER ACTIVITY Exxonmobil Chemical Patents Inc. (US) 2004-09-29 EP disclosed
US-5145818-A OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR THE POLYMERIZATION OF OLEFINS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-09-08 US disclosed
US-5120696-A OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR THE POLYMERIZATION OF OLEFINS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-06-09 US disclosed
US-5091352-A An organoalulminum oxy-compound prepared by treating an alumoxane with water or an alcohol; benzene insolubility MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-02-25 US disclosed
EP-0447035-A2 Method for the preparation of ethylene polymer compositions MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-09-18 EP disclosed
EP-0442725-A2 Olefin polymerization solid catalysts and process for the polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-08-21 EP disclosed
EP-0439964-A2 Olefin polymerization catalyst and process for the polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-08-07 EP disclosed
EP-0436399-A2 Olefin polymerization catalyst and process for the polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-10 EP disclosed
US-4990640-A Polymerization catalyst for alpha-olefin hydrocarbon MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-02-05 US disclosed
EP-0363029-A2 Olefin polymerization catalyst component, olefin polymerization catalyst and process for the polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-04-11 EP disclosed
EP-0360492-A2 Benzene-insoluble organo-aluminum oxy-compounds and process for preparing same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-03-28 EP disclosed