Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | MALT1 | Q9UDY8 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680833 | 0.99 | PTGS1 (0.55) | PTGS1PTGS2MALT1KDM4EPDE4D | |
| SCHEMBL6132456 | 0.89 | PTGS2 (0.67) | PTGS1PTGS2MALT1PDE4DL3MBTL1 | |
| SCHEMBL6687277 | 0.87 | PTGS2 (0.51) | PTGS1PTGS2MALT1KDM4EPDE4D | |
| SCHEMBL6681046 | 0.86 | PTGS2 (0.60) | PTGS1PTGS2MALT1PDE4DL3MBTL1 | |
| SCHEMBL6687447 | 0.84 | PTGS1 (0.57) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL6686639 | 0.83 | RAB9A (0.53) | PTGS1PTGS2MALT1ALDH1A1HPGD | |
| SCHEMBL4247525 | 0.80 | PTGS2 (0.55) | PTGS1PTGS2 | |
| SCHEMBL3356012 | 0.80 | PTGS2 (0.54) | PTGS1PTGS2 | |
| SCHEMBL6680320 | 0.79 | PTGS1 (0.58) | PTGS1PTGS2MALT1KDM4EL3MBTL1 | |
| SCHEMBL6682093 | 0.78 | MALT1 (0.41) | PTGS1PTGS2MALT1PDE4DL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |