Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.38 |
| ▸ | OXTR | P30559 | 2/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686621 | 0.90 | PTGS1 (0.54) | PTGS1PTGS2MERTKNPC1RAB9A | |
| SCHEMBL6682517 | 0.86 | PTGS1 (0.41) | PTGS1PTGS2MEN1KMT2APABPC1 | |
| SCHEMBL6687111 | 0.85 | PTGS1 (0.52) | PTGS1PTGS2NPC1RAB9AL3MBTL1 | |
| SCHEMBL6691220 | 0.84 | PTGS1 (0.63) | PTGS1PTGS2MEN1KMT2APABPC1 | |
| SCHEMBL6687139 | 0.84 | MEN1 (0.48) | PTGS1PTGS2MEN1KMT2APABPC1 | |
| SCHEMBL6689709 | 0.80 | PTGS1 (0.46) | PTGS1PTGS2MEN1KMT2APABPC1 | |
| SCHEMBL6687131 | 0.76 | PTGS1 (0.60) | PTGS1PTGS2L3MBTL1 | |
| SCHEMBL6684498 | 0.76 | KMT2A (0.48) | MEN1KMT2APABPC1NPC1RAB9A | |
| SCHEMBL6684522 | 0.76 | MEN1 (0.48) | PTGS2MEN1KMT2APABPC1NPC1 | |
| SCHEMBL6686978 | 0.75 | MEN1 (0.46) | PTGS2MEN1KMT2APABPC1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |