Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6684498 | 0.87 | KMT2A (0.48) | MEN1PABPC1KMT2AL3MBTL1MDM2 | |
| SCHEMBL6680338 | 0.87 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6686978 | 0.86 | MEN1 (0.46) | MEN1PABPC1KMT2AL3MBTL1MDM2 | |
| SCHEMBL6687276 | 0.85 | L3MBTL1 (0.42) | MEN1KMT2AL3MBTL1ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6685425 | 0.84 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6687139 | 0.84 | MEN1 (0.48) | MEN1PABPC1KMT2AL3MBTL1MDM2 | |
| SCHEMBL6689709 | 0.80 | PTGS1 (0.46) | MEN1PABPC1KMT2AL3MBTL1MDM2 | |
| SCHEMBL4988288 | 0.78 | MEN1 (0.48) | MEN1PABPC1KMT2AL3MBTL1ACACB | |
| SCHEMBL5420057 | 0.78 | MEN1 (0.48) | MEN1PABPC1KMT2AL3MBTL1MDM2 | |
| SCHEMBL5784589 | 0.78 | SMN1; SMN2 (0.63) | MEN1KMT2AL3MBTL1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |