Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690184 | 0.90 | L3MBTL1 (0.57) | L3MBTL1MDM2BCL2MCL1SMN1; SMN2 | |
| SCHEMBL6685914 | 0.87 | L3MBTL1 (0.41) | L3MBTL1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6684522 | 0.86 | MEN1 (0.48) | MEN1PABPC1KMT2AL3MBTL1MDM2 | |
| SCHEMBL6684498 | 0.86 | KMT2A (0.48) | MEN1PABPC1KMT2AL3MBTL1MDM2 | |
| Hydrochloric Acid SCHEMBL6686163 | 0.85 | L3MBTL1 (0.42) | L3MBTL1PTGS2OXTR | |
| SCHEMBL6691333 | 0.83 | L3MBTL1 (0.43) | L3MBTL1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6687149 | 0.83 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1PKMPTGS2OXTR | |
| SCHEMBL6687139 | 0.82 | MEN1 (0.48) | MEN1PABPC1KMT2AL3MBTL1MDM2 | |
| SCHEMBL6687312 | 0.82 | L3MBTL1 (0.38) | MEN1KMT2AL3MBTL1ALDH1A1PKM | |
| SCHEMBL6689709 | 0.79 | PTGS1 (0.46) | MEN1PABPC1KMT2AL3MBTL1MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |