Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686314 | 0.90 | L3MBTL1 (0.59) | KMT2AL3MBTL1GABRA2GABRB2ADORA2A | |
| SCHEMBL6684522 | 0.87 | MEN1 (0.48) | KMT2AMEN1PABPC1L3MBTL1MAPT | |
| SCHEMBL6686978 | 0.86 | MEN1 (0.46) | KMT2AMEN1PABPC1L3MBTL1MAPT | |
| SCHEMBL6687139 | 0.84 | MEN1 (0.48) | KMT2AMEN1PABPC1L3MBTL1GABRA2 | |
| SCHEMBL2918050 | 0.83 | MDM2 (0.59) | KMT2AMEN1PABPC1GABRA2GABRA1 | |
| SCHEMBL4988288 | 0.82 | MEN1 (0.48) | KMT2AMEN1PABPC1L3MBTL1NPC1 | |
| SCHEMBL5783615 | 0.80 | L3MBTL1 (0.55) | KMT2AMEN1L3MBTL1MAPTHPGD | |
| SCHEMBL6689709 | 0.80 | PTGS1 (0.46) | KMT2AMEN1PABPC1L3MBTL1GABRA2 | |
| SCHEMBL5425301 | 0.78 | GABRA2 (0.64) | KMT2AMEN1PABPC1L3MBTL1GABRA2 | |
| SCHEMBL5784589 | 0.78 | SMN1; SMN2 (0.63) | KMT2AMEN1L3MBTL1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |