Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503961 | 0.89 | L3MBTL1 (0.77) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 | |
| SCHEMBL3947553 | 0.86 | L3MBTL1 (0.63) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 | |
| SCHEMBL4837994 | 0.84 | L3MBTL1 (0.65) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 | |
| SCHEMBL266662 | 0.81 | L3MBTL1 (0.72) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 | |
| SCHEMBL3409855 | 0.81 | L3MBTL1 (0.67) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 | |
| SCHEMBL1412911 | 0.81 | HTR1A (0.59) | L3MBTL1KDM4EHTTALDH1A1HPGD | |
| SCHEMBL19325893 | 0.81 | L3MBTL1 (0.66) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 | |
| SCHEMBL9836686 | 0.81 | L3MBTL1 (0.61) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 | |
| SCHEMBL29682135 | 0.80 | L3MBTL1 (0.80) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 | |
| SCHEMBL340762 | 0.80 | L3MBTL1 (0.80) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056744-A1 | ADAMANTYL ACETAMIDES AS HYDROXYSTEROID DEHYDROGENASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-07-08 | — | — | WO | claimed |