Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.54 |
| ▸ | CFD | P00746 | 3/20 | 0.52 |
| ▸ | F11 | P03951 | 3/20 | 0.52 |
| ▸ | TPSB2 | P20231 | 3/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.52 |
| ▸ | F7 | P08709 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.47 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503961 | 0.89 | L3MBTL1 (0.77) | L3MBTL1KDM4ECXCL8CFDF11 | |
| SCHEMBL6682898 | 0.86 | L3MBTL1 (0.73) | L3MBTL1KDM4EHTTPOLBSMN1; SMN2 | |
| SCHEMBL5362778 | 0.82 | HTT (0.71) | L3MBTL1KDM4EHTTPOLBSMN1; SMN2 | |
| SCHEMBL7903525 | 0.81 | KDM4E (0.61) | L3MBTL1KDM4EHTTPOLBSMN1; SMN2 | |
| SCHEMBL6975532 | 0.81 | HTT (0.61) | L3MBTL1KDM4EHTTCFDF11 | |
| SCHEMBL3700349 | 0.81 | CXCL8 (0.57) | L3MBTL1KDM4ECXCL8CFDF11 | |
| SCHEMBL15060188 | 0.81 | KDM4E (0.61) | L3MBTL1KDM4EHTTPOLBSMN1; SMN2 | |
| SCHEMBL22209067 | 0.81 | HTT (0.60) | L3MBTL1KDM4EHTTSMN1; SMN2HPGD | |
| SCHEMBL11533135 | 0.81 | HPGD (0.58) | L3MBTL1KDM4ECXCL8CFDF11 | |
| SCHEMBL24725682 | 0.80 | L3MBTL1 (0.65) | L3MBTL1KDM4EHTTCXCL8CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514425-B2 | Short-acting sedative hypnotic agents for anesthesia and sedation | THERAVANCE, INC. (US) | 2009-04-07 | — | — | US | claimed |
| US-20060116424-A1 | Short-acting sedative hypnotic agents for anesthesia and sedation | THERAVANCE BIOPHARMA R&D IP, LLC | 2006-06-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116424-A1 | Short-acting sedative hypnotic agents for anesthesia and sedation | GABRA5, GABRA6, GABRA2 | L3MBTL1 1347/4885KDM4E 1570/4885HTT 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.