Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 7/20 | 0.50 |
| ▸ | TLR4 | O00206 | 2/20 | 0.49 |
| ▸ | TLR2 | O60603 | 2/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.41 |
| ▸ | CCR6 | P51684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682996 | 1.00 | MAPT (0.54) | MAPTNPSR1ALDH1A1LMNAHPGD | |
| SCHEMBL28648605 | 0.79 | RXRA (0.50) | MAPTNPSR1ALDH1A1LMNAHPGD | |
| SCHEMBL29732385 | 0.78 | TSHR (0.48) | ALDH1A1LMNAHPGDSMN1; SMN2HTT | |
| SCHEMBL1932223 | 0.78 | TSHR (0.48) | ALDH1A1LMNAHPGDSMN1; SMN2HTT | |
| SCHEMBL7905215 | 0.78 | TSHR (0.48) | ALDH1A1LMNAHPGDSMN1; SMN2HTT | |
| SCHEMBL9187108 | 0.76 | TSHR (0.46) | ALDH1A1LMNAHPGDSMN1; SMN2HTT | |
| SCHEMBL9814799 | 0.76 | SNCA (0.50) | MAPTSMN1; SMN2MAPK1HTTFBP1 | |
| SCHEMBL9814803 | 0.76 | SNCA (0.50) | MAPTSMN1; SMN2MAPK1HTTFBP1 | |
| SCHEMBL2541206 | 0.75 | MAPT (0.48) | MAPTNPSR1ALDH1A1LMNAHPGD | |
| SCHEMBL2541208 | 0.75 | MAPT (0.48) | MAPTNPSR1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117113-B | Polysubstituted carbazole, derivative and its synthetic method | 湘潭大学 | 2019-08-16 | — | — | CN | disclosed |
| WO-2004030637-A2 | TREATMENT OF OBESITY AND OTHER DISORDERS ASSOCIATED WITH EXCESSIVE FOOD INTAKE | MERCK & CO., INC. (US) | 2004-04-15 | — | — | WO | disclosed |