Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.72 |
| ▸ | NPC1 | O15118 | 9/20 | 0.72 |
| ▸ | MAPT | P10636 | 8/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | CASP3 | P42574 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921287 | 0.86 | RAB9A (0.82) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4508204 | 0.84 | RAB9A (0.81) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6818506 | 0.82 | RAB9A (0.61) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30002727 | 0.81 | RAB9A (0.70) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6686868 | 0.81 | RAB9A (0.74) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29531637 | 0.81 | RAB9A (0.67) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4512191 | 0.81 | RAB9A (0.67) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28686681 | 0.81 | RAB9A (0.70) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6682494 | 0.81 | RAB9A (0.67) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4510136 | 0.81 | RAB9A (0.65) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067480-A2 | SUBSTITUTED PHENYLUREA DERIVATIVES AS HDAC INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-08-12 | — | — | WO | disclosed |
| WO-2004067480-A2 | SUBSTITUTED PHENYLUREA DERIVATIVES AS HDAC INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-08-12 | — | — | WO | disclosed |