Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.65 |
| ▸ | NPC1 | O15118 | 9/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | MMP13 | P45452 | 2/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683987 | 0.88 | RAB9A (0.63) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL7921287 | 0.86 | RAB9A (0.82) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL5378778 | 0.84 | RAB9A (0.70) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL4508204 | 0.84 | RAB9A (0.81) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL6686868 | 0.81 | RAB9A (0.74) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL29531637 | 0.81 | RAB9A (0.67) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL4512191 | 0.81 | RAB9A (0.67) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL30002727 | 0.81 | RAB9A (0.70) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL28686681 | 0.81 | RAB9A (0.70) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL6682494 | 0.81 | RAB9A (0.67) | RAB9ANPC1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | IL4I1, EPX, IL4 | RAB9A 3680/4885NPC1 4501/4885MAPT 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.