Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | FABP3 | P05413 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154986 | 0.71 | GUSB (0.47) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL6154609 | 0.63 | GUSB (0.59) | KDM4EMAPTALDH1A1L3MBTL1GAA | |
| SCHEMBL3078778 | 0.62 | ENPP2 (0.58) | KDM4EALDH1A1MAPK1FABP3FABP4 | |
| SCHEMBL16029956 | 0.60 | MAPT (0.38) | KDM4EMAPTALDH1A1L3MBTL1GAA | |
| SCHEMBL28897577 | 0.60 | ENPP2 (0.47) | ALDH1A1GAAMAPK1MEN1KMT2A | |
| SCHEMBL26092700 | 0.59 | TDO2 (0.40) | FABP3FABP4FABP5APP | |
| SCHEMBL30296284 | 0.58 | TDO2 (0.40) | KDM4EMAPTALDH1A1FABP3FABP4 | |
| SCHEMBL980630 | 0.56 | MAP4K4 (0.50) | KDM4EMAPTALDH1A1GAAMEN1 | |
| SCHEMBL3191645 | 0.55 | ENPP2 (0.54) | KDM4EMAPTALDH1A1GAAMEN1 | |
| SCHEMBL298552 | 0.55 | ENPP2 (0.54) | ALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446110-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | Structural Bioinformatics Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003032916-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | STRUCTURAL BIOINFORMATICS INC. (US) | 2003-04-24 | — | — | WO | disclosed |