Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680656 | 0.79 | MAPK1 (0.33) | — | |
| SCHEMBL13525787 | 0.76 | ALDH1A1 (0.32) | LMNA | |
| SCHEMBL6681725 | 0.72 | NPC1 (0.32) | TSHRRAB9ANPC1 | |
| SCHEMBL6204718 | 0.72 | NPC1 (0.32) | TSHRRAB9ANPC1 | |
| SCHEMBL6204909 | 0.71 | NPC1 (0.31) | TSHRRAB9ANPC1 | |
| SCHEMBL6677993 | 0.70 | LMNA (0.37) | TSHRRAB9ALMNA | |
| SCHEMBL6682537 | 0.69 | TSHR (0.42) | TSHRRAB9ANPC1LMNA | |
| SCHEMBL1196057 | 0.68 | ALDH1A1 (0.49) | TSHRRAB9ANPC1LMNA | |
| SCHEMBL6203548 | 0.68 | — | — | |
| SCHEMBL6204906 | 0.67 | EPHX2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232276-A1 | Polymers derived from fluoroalkyl norbornenes, fluorinated crotonates, and/or fluorinated allyl alcohols; Diels Alder reaction of a fluorinated crotonate with cyclopentadiene to form said norbornene; photoresists; dielectrics, light guides | HONEYWELL INTERNATIONAL INC. | 2003-12-18 | — | — | US | claimed |
| EP-1476788-A2 | FLUORINATED MOLECULES AND METHODS OF MAKING AND USING SAME | Honeywell International Inc. (US) | 2004-11-17 | — | — | EP | disclosed |
| US-20030232276-A1 | Polymers derived from fluoroalkyl norbornenes, fluorinated crotonates, and/or fluorinated allyl alcohols; Diels Alder reaction of a fluorinated crotonate with cyclopentadiene to form said norbornene; photoresists; dielectrics, light guides | HONEYWELL INTERNATIONAL INC. | 2003-12-18 | — | — | US | disclosed |
| WO-2003073169-A2 | FLUORINATED MOLECULES AND METHODS OF MAKING AND USING SAME | HONEYWELL INTERNATIONAL INC. (US) | 2003-09-04 | — | — | WO | disclosed |