SCHEMBL6680656

SCHEMBL6680656

CC(C)(C)OC(=O)C1C2C=CC(C2)C1(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13525782 0.85 ALDH1A1 (0.33)
SCHEMBL13525787 0.80 ALDH1A1 (0.32)
SCHEMBL6683079 0.79 TSHR (0.34)
SCHEMBL13525798 0.69
SCHEMBL6201818 0.69
SCHEMBL13526000 0.68 CHRM2 (0.33) MAPK1
SCHEMBL13526451 0.68 NR1H2 (0.31)
SCHEMBL6677993 0.66 LMNA (0.37)
SCHEMBL1409756 0.66 ALDH1A1 (0.41) MAPK1
SCHEMBL5838831 0.65 MAPK1 (0.33) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1476788-A2 FLUORINATED MOLECULES AND METHODS OF MAKING AND USING SAME Honeywell International Inc. (US) 2004-11-17 EP disclosed
US-20030232276-A1 Polymers derived from fluoroalkyl norbornenes, fluorinated crotonates, and/or fluorinated allyl alcohols; Diels Alder reaction of a fluorinated crotonate with cyclopentadiene to form said norbornene; photoresists; dielectrics, light guides HONEYWELL INTERNATIONAL INC. 2003-12-18 US disclosed
WO-2003073169-A2 FLUORINATED MOLECULES AND METHODS OF MAKING AND USING SAME HONEYWELL INTERNATIONAL INC. (US) 2003-09-04 WO disclosed