SCHEMBL6683362

SCHEMBL6683362

O=C(O)C1(CO)C2C=CC(C2)C1C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7699416 0.67 ALDH1A1 (0.36) MEN1ALDH1A1POLBKMT2ACTDSP1
SCHEMBL5857255 0.65
SCHEMBL14599395 0.64
SCHEMBL6204718 0.62 NPC1 (0.32)
SCHEMBL6681725 0.62 NPC1 (0.32)
SCHEMBL14468508 0.61
SCHEMBL6685650 0.60
SCHEMBL7940881 0.60 TDP1 (0.39) MEN1ALDH1A1POLBKMT2ACTDSP1
SCHEMBL9792100 0.60 ALDH1A1 (0.50) MEN1ALDH1A1POLBKMT2ACTDSP1
SCHEMBL2476476 0.59 ALDH1A1 (0.32) MEN1ALDH1A1POLBKMT2ACTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1476788-A2 FLUORINATED MOLECULES AND METHODS OF MAKING AND USING SAME Honeywell International Inc. (US) 2004-11-17 EP claimed
US-20030232276-A1 Polymers derived from fluoroalkyl norbornenes, fluorinated crotonates, and/or fluorinated allyl alcohols; Diels Alder reaction of a fluorinated crotonate with cyclopentadiene to form said norbornene; photoresists; dielectrics, light guides HONEYWELL INTERNATIONAL INC. 2003-12-18 US claimed
WO-2003073169-A2 FLUORINATED MOLECULES AND METHODS OF MAKING AND USING SAME HONEYWELL INTERNATIONAL INC. (US) 2003-09-04 WO claimed
US-20030232276-A1 Polymers derived from fluoroalkyl norbornenes, fluorinated crotonates, and/or fluorinated allyl alcohols; Diels Alder reaction of a fluorinated crotonate with cyclopentadiene to form said norbornene; photoresists; dielectrics, light guides HONEYWELL INTERNATIONAL INC. 2003-12-18 US disclosed