Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.60 |
| ▸ | MALT1 | Q9UDY8 | 13/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681259 | 0.89 | PTGS2 (0.53) | PTGS2PTGS1MALT1L3MBTL1 | |
| SCHEMBL6683365 | 0.85 | PTGS1 (0.67) | PTGS2PTGS1MALT1L3MBTL1 | |
| SCHEMBL6685203 | 0.83 | PTGS2 (0.74) | PTGS2PTGS1MALT1L3MBTL1 | |
| SCHEMBL6687277 | 0.83 | PTGS2 (0.51) | PTGS2PTGS1MALT1L3MBTL1 | |
| SCHEMBL6683372 | 0.82 | PTGS1 (0.69) | PTGS2PTGS1MALT1L3MBTL1 | |
| SCHEMBL6684663 | 0.80 | PTGS1 (0.62) | PTGS2PTGS1MALT1L3MBTL1 | |
| SCHEMBL4031131 | 0.78 | PTGS2 (0.81) | PTGS2PTGS1MALT1L3MBTL1 | |
| SCHEMBL6680320 | 0.77 | PTGS1 (0.58) | PTGS2PTGS1MALT1L3MBTL1 | |
| SCHEMBL4032188 | 0.77 | PTGS1 (0.72) | PTGS2PTGS1MALT1L3MBTL1 | |
| SCHEMBL6684037 | 0.75 | PTGS2 (0.72) | PTGS2PTGS1MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |