Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 1.00 |
| ▸ | DRD3 | P35462 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | ACHE | P22303 | 1/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.98 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.98 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.80 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethobenzamide SCHEMBL28858 | 1.00 | DRD2 (1.00) | DRD2DRD3LMNAACHESLC6A2 | |
| Trimethobenzamide SCHEMBL4586290 | 0.99 | DRD2 (0.98) | DRD2DRD3LMNAACHESLC6A2 | |
| Trimethobenzamide SCHEMBL4586216 | 0.99 | SMN1; SMN2 (1.00) | DRD2DRD3LMNAACHESLC6A2 | |
| Trimethobenzamide SCHEMBL4586062 | 0.99 | DRD2 (0.98) | DRD2DRD3LMNAACHESLC6A2 | |
| Trimethobenzamide SCHEMBL41339 | 0.99 | SMN1; SMN2 (1.00) | DRD2DRD3LMNAACHESLC6A2 | |
| Trimethobenzamide SCHEMBL3059009 | 0.98 | DRD2 (0.96) | DRD2DRD3LMNAACHESLC6A2 | |
| Trimethobenzamide SCHEMBL4586023 | 0.97 | DRD2 (0.94) | DRD2DRD3LMNAACHESLC6A2 | |
| Trimethobenzamide SCHEMBL4586233 | 0.96 | DRD2 (0.92) | DRD2DRD3LMNAACHESLC6A2 | |
| Itopride SCHEMBL311309 | 0.89 | DRD2 (1.00) | DRD2DRD3LMNAACHESLC6A2 | |
| Itopride SCHEMBL554675 | 0.88 | DRD2 (0.98) | DRD2DRD3LMNAACHESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471889-A2 | ORAL PEDIATRIC TRIMETHOBENZAMIDE FORMULATIONS AND METHODS | King Pharmaceuticals, Inc. (US) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003072021-A2 | ORAL PEDIATRIC TRIMETHOBENZAMIDE FORMULATIONS AND METHODS | KING PHARMACEUTICALS, INC. (US) | 2003-09-04 | — | — | WO | disclosed |