Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679211 | 0.82 | PTPRA (0.46) | L3MBTL1PTPRANPC1MAOAMAOB | |
| SCHEMBL27910723 | 0.73 | TSHR (0.42) | L3MBTL1NPC1ADORA3TSHRCYP1A2 | |
| SCHEMBL6683522 | 0.73 | LMNA (0.39) | L3MBTL1SLC6A2TSHRCYP1A2LMNA | |
| SCHEMBL27747236 | 0.71 | GRIN2B (0.43) | NPC1TSHRCYP1A2GRIN2BSCN9A | |
| SCHEMBL29112408 | 0.71 | MAPT (0.46) | NPC1SLC6A2SCN9ALMNARAB9A | |
| SCHEMBL27726323 | 0.71 | MAPT (0.46) | NPC1SLC6A2SCN9ALMNARAB9A | |
| SCHEMBL27726319 | 0.71 | MAPT (0.46) | NPC1SLC6A2SCN9ALMNARAB9A | |
| SCHEMBL10290171 | 0.71 | SMN1; SMN2 (0.62) | L3MBTL1NPC1PGRADORA3PTGS1 | |
| SCHEMBL27454529 | 0.70 | ADRB2 (0.38) | NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL28862367 | 0.69 | MAPT (0.47) | NPC1SCN9ALMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |