Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679213 | 0.82 | CYP2D6 (0.48) | LMNATSHRALDH1A1CYP3A4KDM4E | |
| SCHEMBL28752161 | 0.77 | SYK (0.42) | LMNATSHRALDH1A1CYP3A4KDM4E | |
| SCHEMBL6500322 | 0.73 | SIRT1 (0.39) | SMN1; SMN2 | |
| SCHEMBL6683519 | 0.73 | L3MBTL1 (0.40) | LMNATSHRRAB9ACYP1A2SLC6A2 | |
| SCHEMBL9530814 | 0.72 | SLC6A2 (0.46) | LMNATSHRALDH1A1CYP3A4KDM4E | |
| SCHEMBL27910723 | 0.71 | TSHR (0.42) | LMNATSHRALDH1A1CYP3A4KDM4E | |
| SCHEMBL27770762 | 0.71 | MAPT (0.46) | LMNACYP1A2NPSR1MEN1KMT2A | |
| SCHEMBL7084236 | 0.70 | SLC6A2 (0.53) | LMNATSHRALDH1A1CYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL29221336 | 0.70 | ALDH1A1 (0.49) | LMNATSHRALDH1A1CYP3A4KDM4E | |
| SCHEMBL6831204 | 0.70 | SLC6A2 (0.40) | LMNATSHRALDH1A1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |