Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681177 | 0.88 | ADORA3 (0.51) | ADORA3NPSR1NPC1POLBRAB9A | |
| SCHEMBL6683419 | 0.86 | ADORA3 (0.50) | ADORA3NPSR1NPC1POLBRAB9A | |
| SCHEMBL6683539 | 0.82 | ADORA3 (0.54) | ADORA3NPSR1NPC1POLBRAB9A | |
| SCHEMBL6680339 | 0.77 | ADORA3 (0.66) | ADORA3NPSR1NPC1RAB9AMAPT | |
| SCHEMBL6678678 | 0.76 | ADORA3 (0.60) | ADORA3NPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL6681714 | 0.76 | ADORA3 (0.61) | ADORA3NPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL6681064 | 0.75 | ALDH1A1 (0.69) | ADORA3NPSR1NPC1POLBRAB9A | |
| SCHEMBL6681136 | 0.73 | MEN1 (0.57) | ADORA3NPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL6684117 | 0.72 | ALDH1A1 (0.69) | ADORA3NPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL6681047 | 0.72 | MEN1 (0.55) | ADORA3NPSR1MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |