Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4484186 | 0.86 | NR3C1 (0.42) | GAANR3C1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6683637 | 0.81 | ADRB3 (0.45) | GAANPSR1KDRADRB3 | |
| SCHEMBL4635188 | 0.72 | NR3C1 (0.40) | GAANR3C1KMT2AKDM4EHPGD | |
| SCHEMBL4484871 | 0.72 | KDM4E (0.44) | NR3C1KMT2AKDM4EALDH1A1ACHE | |
| SCHEMBL4486735 | 0.72 | NR3C1 (0.40) | NR3C1ACHEBCHESIGMAR1 | |
| SCHEMBL1120902 | 0.71 | NR3C1 (0.42) | GAANR3C1KDM4EALDH1A1 | |
| SCHEMBL1120907 | 0.69 | ESR1 (0.41) | NR3C1 | |
| SCHEMBL1120793 | 0.68 | NR3C1 (0.39) | NR3C1ADRB3 | |
| SCHEMBL4513404 | 0.68 | NR3C1 (0.39) | NR3C1 | |
| SCHEMBL4484184 | 0.67 | ADRB3 (0.62) | ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1447400-A1 | BICYCLIC COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2004-08-18 | — | — | EP | claimed |