SCHEMBL668366

SCHEMBL668366

CCO[Si](OCC)(OCC)c1ccccc1CCl

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
NFKB1 P19838 1/20 0.31
CYP2C19 P33261 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
LMNA P02545 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8371251 0.87 LTA4H (0.33) TP53
SCHEMBL8371242 0.85 NR1I2 (0.33) TSHRALDH1A1KMT2ALMNA
SCHEMBL3713760 0.84 MAPT (0.40) TSHRALDH1A1TP53MAPTNPSR1
SCHEMBL3458353 0.84 CYP4F2 (0.33) MAPTNPSR1L3MBTL1
SCHEMBL18037943 0.82 TP53 (0.30) TP53
SCHEMBL331176 0.81 ALDH1A1 (0.33) TSHRALDH1A1TP53CYP1A2NPSR1
SCHEMBL29520127 0.81 ALDH1A1 (0.33) TSHRALDH1A1TP53CYP1A2NPSR1
SCHEMBL2524732 0.81 IDO1 (0.38) MAPTNPSR1L3MBTL1
SCHEMBL27943311 0.81 ADRA2B (0.36) ALDH1A1MAPTNPSR1L3MBTL1
SCHEMBL28045163 0.81 ELANE (0.34) TSHRMAPTCYP1A2CYP2D6NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874674-B Large-area hydrophilic polymer brush coating layer and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2023-05-16 CN claimed
US-10766913-B2 Mixtures of cyclic branched siloxanes of the D/T type and conversion products thereof EVONIK OPERATIONS GMBH (DE) 2020-09-08 US disclosed
US-10414871-B2 Mixtures of cyclic branched siloxanes of the D/T type and conversion products thereof EVONIK DEGUSSA GMBH (DE) 2019-09-17 US disclosed
US-10399998-B2 Mixtures of cyclic branched siloxanes of the D/T type and conversion products thereof EVONIK DEGUSSA GMBH (DE) 2019-09-03 US disclosed
EP-1892089-B1 GAS BARRIER LAMINATE, METHOD FOR PRODUCING SAME AND PACKAGE BODY USING SAME KURARAY CO (JP) 2019-05-29 EP disclosed
US-20190106441-A1 Mixtures Of Cyclic Branched Siloxanes Of The D/T Type And Conversion Products Thereof EVONIK DEGUSSA GMBH (DE) 2019-04-11 US disclosed
US-20180319823-A1 MIXTURES OF CYCLIC BRANCHED SILOXANES OF THE D/T TYPE AND CONVERSION PRODUCTS THEREOF EVONIK OPERATIONS GMBH (DE) 2018-11-08 US disclosed
CN-108070086-A The mixture and its converted product of the siloxanes of D/T type ring shape cladodification 赢创德固赛有限公司 2018-05-25 CN disclosed
US-20180134850-A1 MIXTURES OF CYCLIC BRANCHED SILOXANES OF THE D/T TYPE AND CONVERSION PRODUCTS THEREOF EVONIK OPERATIONS GMBH (DE) 2018-05-17 US disclosed
EP-1690678-B1 GAS BARRIER LAMINATE AND PACKAGED ARTICLE, AND METHOD FOR PRODUCING GAS BARRIER LAMINATE KURARAY CO (JP) 2016-09-14 EP disclosed
US-20090050020-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2009-02-26 US disclosed
US-20090030126-A1 food packagings; oxygen barrier property independent of humidity; disposability, waterproofing, high transparency, excellent mechanical properties; neutralize a hydrolyzed and condensed product of tetramethoxysilane, 3-mercaptopropyltrimethoxysilane, and titanium tetraisopropoxide, polyacrylic acid KURARAY CO., LTD. (JP) 2009-01-29 US disclosed
EP-1892089-A1 GAS BARRIER LAMINATE, METHOD FOR PRODUCING SAME AND PACKAGE BODY USING SAME Kuraray Co., Ltd., Kurashiki Plant (JP) 2008-02-27 EP disclosed
EP-1630206-B1 Opacifying particles ROHM & HAAS (US) 2007-12-05 EP disclosed
EP-1855159-A1 COMPOSITION FOR UNDERLAYER FILM OF RESIST AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2007-11-14 EP disclosed
US-20070111005-A1 Gas barrier laminate and packaged article, and method for producing gas barrier laminate KURARAY CO., LTD. (JP) 2007-05-17 US disclosed
EP-1690678-A1 GAS BARRIER LAMINATE AND PACKAGED ARTICLE, AND METHOD FOR PRODUCING GAS BARRIER LAMINATE KURARAY CO., LTD. (JP) 2006-08-16 EP disclosed
EP-1630206-A2 Opacifying particles Rohm and Haas Company (US) 2006-03-01 EP disclosed
US-20060009546-A1 Opacifying particles ROHM AND HAAS CO. 2006-01-12 US disclosed
CN-1718604-A Light-screening microparticles ROHM & HAAS (US) 2006-01-11 CN disclosed