SCHEMBL66837

SCHEMBL66837

COc1cc(CCl)c([N+](=O)[O-])cc1OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
CYP2D6 P10635 1/20 0.56
RAB9A P51151 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
NPC1 O15118 2/20 0.54
KDM4E B2RXH2 3/20 0.53
CYP3A4 P08684 3/20 0.53
MAPT P10636 2/20 0.53
ALOX15 P16050 1/20 0.53
PRKDC P78527 1/20 0.53
HSD17B10 Q99714 1/20 0.53
CYP2C19 P33261 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
TDP1 Q9NUW8 2/20 0.48
HTT P42858 1/20 0.48
LMNA P02545 1/20 0.48
HPGD P15428 1/20 0.48
CYP1A2 P05177 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7417187 0.88 ALDH1A1 (0.48) ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2
SCHEMBL14410938 0.85 RAB9A (0.45) ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2
SCHEMBL124590 0.85 ALDH1A1 (0.63) ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2
SCHEMBL3645769 0.85 ALDH1A1 (0.59) ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2
SCHEMBL4043187 0.84 ALDH1A1 (0.57) ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2
SCHEMBL9392804 0.83 ALDH1A1 (0.51) ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2
SCHEMBL40798 0.82 ALDH1A1 (0.56) ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2
SCHEMBL1261460 0.82 ALDH1A1 (0.56) ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2
SCHEMBL5058658 0.82 ALDH1A1 (0.56) ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2
SCHEMBL12978933 0.82 ALDH1A1 (0.56) ALDH1A1L3MBTL1CYP2D6RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230202221-A1 THERMAL TRANSFER SHEET, DISCOLORED OR DECOLORIZED PRINTED MATERIAL, AND METHOD FOR PRODUCING DISCOLORED OR DECOLORIZED PRINTED MATERIAL DAI NIPPON PRINTING CO., LTD. (JP) 2023-06-29 US disclosed
US-9416289-B2 Active-energy-ray-curable inkjet ink composition, active-energy-ray-curable inkjet ink, and inkjet recording method Konica Minolta, Inc. (JP) 2016-08-16 US disclosed
US-8454152-B2 Ink jet recording device and ink jet recording method KONICA MINOLTA HOLDINGS, INC. (JP) 2013-06-04 US disclosed
US-8439480-B2 Ink jet recording apparatus, and ink jet recording method KONICA MINOLTA HOLDINGS, INC. (JP) 2013-05-14 US disclosed
EP-1865379-B1 Method for resist pattern formation, and process for device prodution CANON KK (JP) 2013-01-16 EP disclosed
CN-102883773-A Phototriggered nanoparticles for cell and tissue targeting MASSACHUSETTS INST TECHNOLOGY 2013-01-16 CN disclosed
US-8349916-B2 Actinic energy radiation curable ink-jet ink, ink-jet recording method, and printed matter KONICA MINOLTA IJ TECHNOLOGIES, INC. (JP) 2013-01-08 US disclosed
US-20130004522-A1 PHOTOTRIGGERED NANOPARTICLES FOR CELL AND TISSUE TARGETING NIH-DEITR 2013-01-03 US disclosed
EP-2482922-A1 PHOTOTRIGGERED NANOPARTICLES FOR CELL AND TISSUE TARGETING Massachusetts Institute of Technology (US) 2012-08-08 EP disclosed
US-8129087-B2 Block copolymer and substrate processing method CANON KABUSHIKI KAISHA (JP) 2012-03-06 US disclosed
WO-1994021612-A1 CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-09-29 WO disclosed
US-4859551-A Process for preparing positive and negative images using photohardenable electrostatic master E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-08-22 US disclosed
EP-0315121-A2 Process for preparing positive and negative images using photohardenable electrostatic master E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-05-10 EP disclosed
EP-0103197-B1 ACIDIC O-NITROAROMATICS AS PHOTOINHIBITORS OF POLYMERIZATION IN POSITIVE WORKING FILMS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-01-22 EP disclosed
US-4511641-A Metal film imaging structure MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-04-16 US disclosed
US-4477556-A Acidic o-nitroaromatics as photoinhibitors of polymerization in positive working films E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-16 US disclosed
EP-0103197-A1 Acidic O-nitroaromatics as photoinhibitors of polymerization in positive working films E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-21 EP disclosed
US-4269933-A PHOTOLITHOGRAPHY; POSITIVE AND NEGATIVE IMAGES; POLYMERIZATION OF A UNSATURATED POLYESTER USING A PHOTOSENSITIVE FREE RADICAL SYSTEM E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-05-26 US disclosed
US-4198242-A Photopolymerizable composition containing an o-nitroaromatic compound as photoinhibitor E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-04-15 US disclosed
US-3974110-A Modification of polystyrene by Friedel-Crafts reaction with substituted halo ethyl benzenes and haloethylphenols to make supports for solid phase peptide synthesis YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) 1976-08-10 US disclosed