Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | PRKDC | P78527 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18314720 | 0.92 | ALDH1A1 (0.56) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL9348473 | 0.90 | ALDH1A1 (0.51) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL9392804 | 0.90 | ALDH1A1 (0.51) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL12978933 | 0.89 | ALDH1A1 (0.56) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL9348632 | 0.88 | ALDH1A1 (0.53) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL8690 | 0.86 | ALDH1A1 (0.54) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL16033288 | 0.86 | ALDH1A1 (0.54) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL14226424 | 0.86 | RAB9A (0.52) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL28701077 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A | |
| SCHEMBL3119487 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CYP2D6L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716453-A | Macrocyclization reactions and intermediates useful in the synthesis of analogs of halichondrin B | 卫材R&D管理有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-109942560-B | Macrocyclization reactions and intermediates useful in the synthesis of analogs of halichondrin B | 卫材R&D管理有限公司 | 2022-06-17 | — | — | CN | disclosed |
| EP-3116558-B1 | LIGHT-TRIGGERED SHAPE-CHANGEABLE HYDROGELS AND THEIR USE IN OPTICAL DEVICES | CALIFORNIA INST OF TECHN (US) | 2018-10-31 | — | — | EP | disclosed |
| EP-3116558-A1 | LIGHT-TRIGGERED SHAPE-CHANGEABLE HYDROGELS AND THEIR USE IN OPTICAL DEVICES | California Institute of Technology (US) | 2017-01-18 | — | — | EP | disclosed |
| US-20150258240-A1 | LIGHT-TRIGGERED SHAPE-CHANGEABLE HYDROGELS AND THEIR USE IN OPTICAL DEVICES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2015-09-17 | — | — | US | disclosed |
| WO-2015138187-A1 | LIGHT-TRIGGERED SHAPE-CHANGEABLE HYDROGELS AND THEIR USE IN OPTICAL DEVICES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-09-17 | — | — | WO | disclosed |
| US-7393515-B2 | Fluorinated compound, water repellent composition and thin film | ASAHI GLASS COMPANY, LIMITED (JP) | 2008-07-01 | — | — | US | disclosed |
| EP-1736477-A1 | FLUORINE-CONTAINING COMPOUND, WATER REPELLENT COMPOSITION AND THIN FILM | Asahi Glass Company, Limited (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-20060222865-A1 | Fluorinated compound, water repellent composition and thin film | ASAHI GLASS COMPANY, LIMITED (JP) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060222865-A1 | Fluorinated compound, water repellent composition and thin film | AFF1, FLOT1, AFF2 | ALDH1A1 2644/4885CYP2D6 3361/4885L3MBTL1 694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.