Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.68 |
| ▸ | AHCY | P23526 | 5/20 | 0.65 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11410351 | 0.90 | AHCY (0.67) | ADORA3ADORA2BAHCYHSP90B1ADORA2A | |
| SCHEMBL11131647 | 0.90 | AHCY (0.67) | ADORA3ADORA2BAHCYHSP90B1ADORA2A | |
| SCHEMBL9493927 | 0.90 | ADORA3 (0.70) | ADORA3ADORA2BAHCYHSP90B1ADORA2A | |
| SCHEMBL11408861 | 0.89 | ADORA3 (0.67) | ADORA3ADORA2BAHCYHSP90B1ADORA2A | |
| SCHEMBL11407181 | 0.88 | ADORA3 (0.70) | ADORA3ADORA2BAHCYHSP90B1ADORA2A | |
| SCHEMBL11421032 | 0.88 | ADORA3 (0.64) | ADORA3ADORA2BAHCYHSP90B1ADORA2A | |
| SCHEMBL11409857 | 0.88 | ADORA3 (0.70) | ADORA3ADORA2BAHCYHSP90B1ADORA2A | |
| SCHEMBL11413667 | 0.87 | ADORA2B (0.69) | ADORA3ADORA2BAHCYHSP90B1ADORA2A | |
| SCHEMBL1000839 | 0.87 | ADORA2B (0.69) | ADORA3ADORA2BAHCYHSP90B1ADORA2A | |
| SCHEMBL11409572 | 0.85 | HSP90B1 (0.59) | ADORA3ADORA2BAHCYHSP90B1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1469864-A1 | COMPOUNDS USEFUL AS A-3 ADENOSINE RECEPTOR AGONISTS | MUSCAGEN LIMITED (GB) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003061670-A1 | COMPOUNDS USEFUL AS A3 ADENOSINE RECEPTOR AGONISTS | MUSCAGEN LIMITED (GB) | 2003-07-31 | — | — | WO | disclosed |