SCHEMBL6684419

SCHEMBL6684419

O=C(O)C(Cc1ccccc1)C(O)C1CC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.54
SLC1A2 P43004 1/20 0.54
SLC1A1 P43005 1/20 0.54
CYP1A2 P05177 1/20 0.48
LMNA P02545 2/20 0.46
PKM P14618 2/20 0.46
ALPI P09923 1/20 0.46
PTGS1 P23219 1/20 0.46
XIAP P98170 1/20 0.46
SLC7A5 Q01650 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CPA1 P15085 3/20 0.43
CPA3 P15088 3/20 0.43
FOLH1 Q04609 1/20 0.43
CPB1 P15086 1/20 0.43
CPB2 Q96IY4 1/20 0.43
SRR Q9GZT4 2/20 0.42
ALDH1A1 P00352 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL7289849 0.79 SLC1A3 (0.73) SLC1A3SLC1A2SLC1A1CYP1A2PKM
(2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL305323 0.79 SLC1A3 (0.73) SLC1A3SLC1A2SLC1A1CYP1A2PKM
(2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL4755513 0.79 SLC1A3 (0.73) SLC1A3SLC1A2SLC1A1CYP1A2PKM
(2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL2919214 0.79 SLC1A3 (0.73) SLC1A3SLC1A2SLC1A1CYP1A2PKM
SCHEMBL7269073 0.77 SLC1A3 (0.66) SLC1A3SLC1A2SLC1A1CYP1A2PKM
SCHEMBL7436297 0.76 SLC1A3 (0.63) SLC1A3SLC1A2SLC1A1CYP1A2PKM
SCHEMBL2243422 0.76 SLC1A3 (0.63) SLC1A3SLC1A2SLC1A1CYP1A2PKM
SCHEMBL3866544 0.76 SLC1A3 (0.63) SLC1A3SLC1A2SLC1A1CYP1A2PKM
SCHEMBL3867023 0.76 SLC1A3 (0.63) SLC1A3SLC1A2SLC1A1CYP1A2PKM
SCHEMBL24252143 0.74 SLC1A3 (0.61) SLC1A3SLC1A2SLC1A1CYP1A2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1261657-B1 POLY(3-CYCLOPROPYL-3-HYDROXYPROPIONATE) AND PROCESSES FOR ITS PREPARATION AND DERIVATIVES THEREOF EASTMAN CHEM CO (US) 2004-11-10 EP disclosed
US-20040210030-A1 Poly(3-cyclopropyl-3-hydroxypropionate) and processes for its preparation and derivatives thereof HUBBS JOHN CLARK (US) 2004-10-21 US disclosed
US-6710206-B2 HEATING TO DEHYDROGENATE AND FORM 3-CYCLOPROPYLACRYLIC ACID; VINYLCYCLOPROPANE AND CYCLOPROPYLACETYLENE PREPARATION EASTMAN CHEMICAL COMPANY 2004-03-23 US disclosed
US-20030212294-A1 Poly(3-cyclopropyl-3-hydroxypropionate) and processes for its preparation and derivatives thereof HUBBS JOHN CLARK (US) 2003-11-13 US disclosed
US-20030208092-A1 Poly(3-cyclopropyl-3-hydroxypropionate) and processes for its preparation and derivatives thereof HUBBS JOHN CLARK (US) 2003-11-06 US disclosed
US-6610878-B1 Catalytic reaction of cyclopropanecarboxaldehyde and ketene; intermediates to vinylcyclopropane, cyclopropylacetylene and cyclopropylacrylic; inexpensive EASTMAN CHEMICAL COMPANY 2003-08-26 US disclosed
EP-1261657-A2 POLY(3-CYCLOPROPYL-3-HYDROXYPROPIONATE) AND PROCESSES FOR ITS PREPARATION AND DERIVATIVES THEREOF EASTMAN CHEMICAL COMPANY (US) 2002-12-04 EP disclosed
WO-2000068290-A2 POLY(3-CYCLOPROPYL-3-HYDROXYPROPIONATE) AND PROCESSES FOR ITS PREPARATION AND DERIVATIVES THEREOF EASTMAN CHEMICAL COMPANY (US) 2000-11-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030212294-A1 Poly(3-cyclopropyl-3-hydroxypropionate) and processes for its preparation and derivatives thereof HACL2, HPD, GRHPR SLC1A3 1766/4885SLC1A2 3391/4885SLC1A1 1799/4885
US-20030208092-A1 Poly(3-cyclopropyl-3-hydroxypropionate) and processes for its preparation and derivatives thereof HPD, HACL2, GRHPR SLC1A3 1701/4885SLC1A2 3320/4885SLC1A1 1737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.