Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29854261 | 0.78 | TRPA1 (0.41) | TRPA1 | |
| SCHEMBL8276 | 0.78 | TRPA1 (0.41) | TRPA1 | |
| Hydrochloric Acid SCHEMBL10718555 | 0.77 | TRPA1 (0.39) | TRPA1MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL449119 | 0.70 | POLB (0.38) | TRPA1MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL28613397 | 0.68 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL2516584 | 0.67 | MEN1 (0.34) | TRPA1MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL2516583 | 0.67 | TRPA1 (0.38) | TRPA1 | |
| SCHEMBL1238031 | 0.67 | ALDH1A1 (0.40) | TRPA1MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL31001736 | 0.66 | ALDH1A1 (0.48) | MEN1ALDH1A1GAAKMT2ARYR2 | |
| SCHEMBL255970 | 0.66 | ALDH1A1 (0.48) | MEN1ALDH1A1GAAKMT2ARYR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1029847-C | Process for preparing 1, 5-benzothiazepine * derivatives | TANABE SEIYAKU CO (JP) | 1995-09-27 | — | — | CN | claimed |
| CN-1054597-A | Preparation 1, the method for 5-benzothiazepine derivatives | TANABE SEIYAKU CO (JP) | 1991-09-18 | — | — | CN | claimed |
| CN-119698413-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-115518402-B | Toluene chlorination liquid post-treatment device and treatment method | 中盐常州化工股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-116964048-A | Bicyclic tetrahydroazepine derivatives for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-113896612-B | Method for selectively preparing o-chlorotoluene | 常州新东化工发展有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-115518402-A | Toluene chlorination liquid post-treatment device and treatment method | 中盐常州化工股份有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-101735211-B | Applications of 2,3-dihydro[1,5] benzothiazepine compounds or salts thereof in preparation of GSK-3beta inhibitor | UNIV FUDAN | 2012-11-14 | — | — | CN | disclosed |
| CN-101735211-B | Applications of 2,3-dihydro[1,5] benzothiazepine compounds or salts thereof in preparation of GSK-3beta inhibitor | UNIV FUDAN | 2012-11-14 | — | — | CN | disclosed |
| CN-101735211-A | 2, application of 3-dihydro [1,5] benzothiaze compounds or salts thereof in preparing GSK-3 beta inhibitor | UNIV FUDAN | 2010-06-16 | — | — | CN | disclosed |
| CN-1896078-A | Bicyclic pyrrolyl amides as glucogen phosphorylase inhibitors | ASTRAZENECA AB (SE) | 2007-01-17 | — | — | CN | disclosed |
| EP-0638082-A1 | MACROCYCLIC IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1995-02-15 | — | — | EP | disclosed |
| WO-1994021642-A1 | MACROCYCLIC AMIDE AND UREA IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1994-09-29 | — | — | WO | disclosed |
| EP-0642516-A4 | MACROCYCLIC IMMUNOMODULATORS. | ABBOTT LAB (US) | 1994-06-15 | — | — | EP | disclosed |
| EP-0638082-A4 | MACROCYCLIC IMMUNOMODULATORS. | ABBOTT LAB (US) | 1994-06-09 | — | — | EP | disclosed |
| WO-1993004680-A1 | MACROCYCLIC IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1993-03-18 | — | — | WO | disclosed |
| WO-1993004679-A1 | MACROCYCLIC IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1993-03-18 | — | — | WO | disclosed |
| CN-1005150-B | 1, 5-benzothiazepine * derivatives as platelet aggregation inhibitors | 田道制药株式会社 | 1989-09-13 | — | — | CN | disclosed |
| CN-85101892-A | Process for preparing novel 1, 5-benzothiazepine derivatives | — | 1987-01-17 | — | — | CN | disclosed |
| CN-85103395-A | Preparation of 1, 5-benzothiazepine * derivatives as platelet aggregation inhibitors | — | 1986-12-10 | — | — | CN | disclosed |