SCHEMBL8276

SCHEMBL8276

C1=Nc2ccccc2SC1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29854261 1.00 TRPA1 (0.41) TRPA1
Hydrochloric Acid SCHEMBL10718555 0.98 TRPA1 (0.39) TRPA1
SCHEMBL28613397 0.87 TRPA1 (0.33) TRPA1
SCHEMBL6684739 0.78 TRPA1 (0.38) TRPA1
SCHEMBL7627621 0.77 TRPA1 (0.37) TRPA1
SCHEMBL44015 0.71 S100A4 (0.39)
SCHEMBL2516583 0.70 TRPA1 (0.38) TRPA1
SCHEMBL4513308 0.68
SCHEMBL7062214 0.67 TRPA1 (0.44) TRPA1
SCHEMBL1239354 0.66 HTT (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4277 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005810-A Application of peroxide reductase 1 as target in preparation of IS therapeutic drugs 国科宁波生命与健康产业研究院 2026-05-12 CN claimed
EP-4630446-A1 ENGINEERED SWITCHES FOR IMMUNE CELL ACTIVITY AND METHODS OF USE THEREOF Dynamic Cell Therapies, Inc. (US) 2025-10-15 EP claimed
EP-4630043-A1 IMMUNE-ACTIVATING COMPLEXES Dynamic Cell Therapies, Inc. (US) 2025-10-15 EP claimed
CN-116970145-B Amphiphilic triblock polymer, stimulus-responsive nanoparticle and preparation method thereof 中国科学技术大学 2025-06-13 CN claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
CN-120020131-A Aromatic ring benzothiazine derivative and medical application thereof 杭州百诚医药科技股份有限公司 2025-05-20 CN claimed
CN-119745702-A Zirconia ceramic block for manufacturing false tooth 深圳玉汝成口腔材料有限公司 2025-04-04 CN claimed
CN-119744352-A Intracellular ligation of photocatalysts for photoresponsive, probe-mediated protein labeling 美国锡德治疗有限公司 2025-04-01 CN claimed
CN-119504645-A Method for synthesizing N- (acetamidomethyl) benzothiazine-4-ketone 常州大学 2025-02-25 CN claimed
US-20250057874-A1 SYNTHETIC MELANIN NANOPARTICLES AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-20 US claimed
EP-0091044-B1 PROCESS FOR THE PREPARATION OF 4-HYDROXY-3-(HETEROCYCLOCARBAMOYL)-2H-1,2-BENZOTHIAZINE-1,1 DIOXIDES GÖDECKE AKTIENGESELLSCHAFT (DE) 1986-06-18 EP claimed
US-4595685-A Pharmaceuticals HOECHST AKTIENGESELLSCHAFT (DE) 1986-06-17 US claimed
US-4552871-A ALDOSTERONE-ANTAGONISTIC, DIURETICS CIBA GEIGY CORPORATION (US) 1985-11-12 US claimed
EP-0140886-A4 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS. LITTLE INC A (US) 1985-09-02 EP claimed
EP-0042435-B1 BENZOTHIAZINE DERIVATIVES Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1985-06-12 EP claimed
EP-0140886-A1 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS. LITTLE INC A (US) 1985-05-15 EP claimed
US-4490292-A 1,5-Benzothiazepine derivatives and production thereof HAMARI CHEMICALS, LTD. (JP) 1984-12-25 US claimed
WO-1984004165-A1 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS LITTLE INC A (US) 1984-10-25 WO claimed
EP-0042435-A1 BENZOTHIAZINE DERIVATIVES Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1981-12-30 EP claimed
US-4294961-A REMOVAL OF METALS HENKEL CORPORATION (US) 1981-10-13 US claimed