Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18071006 | 0.88 | GAA (0.39) | IDO1NR1H2GAATSHRGLA | |
| SCHEMBL16045315 | 0.85 | NR1H2 (0.42) | IDO1NR1H2GAATSHRGLA | |
| SCHEMBL23287631 | 0.84 | IDO1 (0.43) | IDO1NR1H2MAPTBACE1TACR1 | |
| SCHEMBL30692344 | 0.82 | IDO1 (0.41) | IDO1GAATSHRMAPTMAPK1 | |
| SCHEMBL21163340 | 0.81 | ALDH1A1 (0.39) | GAATSHRKDM4EMEN1ALDH1A1 | |
| SCHEMBL17798345 | 0.79 | BACE1 (0.36) | IDO1GAATSHRMAPTMAPK1 | |
| SCHEMBL2596584 | 0.78 | MAPT (0.56) | IDO1GAATSHRKDM4EALDH1A1 | |
| SCHEMBL2646502 | 0.77 | CYP1A2 (0.34) | GAATSHRMAPTMAPK1HTT | |
| SCHEMBL5462578 | 0.77 | IDO1 (0.45) | IDO1POLBBACE1TACR1 | |
| SCHEMBL30994688 | 0.76 | GAA (0.36) | GAATSHRMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648851-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | Astrazeneca AB (SE) | 2025-11-19 | — | — | EP | disclosed |
| CN-119874606-A | Fused piperidinyl bicyclic and related compounds as modulators of C5a receptors | 因弗拉克斯有限责任公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-113784955-B | Fused piperidinyl bicyclic and related compounds as modulators of C5a receptors | 因弗拉克斯有限责任公司 | 2025-02-14 | — | — | CN | disclosed |
| US-12054488-B2 | Pyrazolopyrimidine compound and preparation method therefor and use thereof in preparation of anti-cancer drug | SUZHOU RAYMON PHARMACEUTICALS COMPANY, LTD. (CN) | 2024-08-06 | — | — | US | disclosed |
| WO-2024149728-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | ASTRAZENECA AB (SE) | 2024-07-18 | — | — | WO | disclosed |
| US-11999698-B2 | Fused piperidinyl bicyclic and related compounds as modulators of C5a receptor | INFLARX GMBH (DE) | 2024-06-04 | — | — | US | disclosed |
| US-11807609-B2 | Deuterated compounds as immunomodulators | CHEMOCENTRYX, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| US-11807609-B2 | Deuterated compounds as immunomodulators | CHEMOCENTRYX, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| CN-112707907-B | Purine derivative and intermediate thereof, and application of purine derivative and intermediate thereof in preparation of anti-cancer drugs | 张飞 | 2023-05-23 | — | — | CN | disclosed |
| US-20220389017-A1 | NOVEL PURINE DERIVATIVE, INTERMEDIATE AND APPLICATION THEREOF IN PREPARING ANTICANCER MEDICINE | SUZHOU RAYMON PHARMACEUTICALS COMPANY, LTD. (CN) | 2022-12-08 | — | — | US | disclosed |
| US-11149009-B2 | Fused piperidinyl bicyclic and related compounds as modulators of C5A receptor | INFLARX GMBH (DE) | 2021-10-19 | — | — | US | disclosed |
| US-20210276955-A1 | DEUTERATED COMPOUNDS AS IMMUNOMODULATORS | CHEMOCENTRYX, INC. | 2021-09-09 | — | — | US | disclosed |
| WO-2021078141-A1 | NOVEL PURINE DERIVATIVE, INTERMEDIATE AND APPLICATION THEREOF IN PREPARING ANTICANCER MEDICINE | 苏州锐明新药研发有限公司 | 2021-04-29 | — | — | WO | disclosed |
| WO-2021078141-A1 | NOVEL PURINE DERIVATIVE, INTERMEDIATE AND APPLICATION THEREOF IN PREPARING ANTICANCER MEDICINE | 苏州锐明新药研发有限公司 | 2021-04-29 | — | — | WO | disclosed |
| US-20200290969-A1 | FUSED PIPERIDINYL BICYCLIC AND RELATED COMPOUNDS AS MODULATORS OF C5A RECEPTOR | INFLARX GMBH (DE) | 2020-09-17 | — | — | US | disclosed |
| US-20200290969-A1 | FUSED PIPERIDINYL BICYCLIC AND RELATED COMPOUNDS AS MODULATORS OF C5A RECEPTOR | INFLARX GMBH (DE) | 2020-09-17 | — | — | US | disclosed |
| WO-2020182384-A1 | FUSED PIPERIDINYL BICYCLIC AND RELATED COMPOUNDS AS MODULATORS OF C5A RECEPTOR | INFLARX GMBH (DE) | 2020-09-17 | — | — | WO | disclosed |
| WO-2020063636-A1 | PYRAZOLOPYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF IN PREPARATION OF ANTI-CANCER DRUG | 苏州锐明新药研发有限公司 | 2020-04-02 | — | — | WO | disclosed |
| US-20190144389-A1 | DEUTERATED COMPOUNDS AS IMMUNOMODULATORS | CHEMOCENTRYX, INC. | 2019-05-16 | — | — | US | disclosed |
| US-20120046467-A1 | QUATERNARY AMMONIUM SALT COMPOUNDS | TEIJIN PHARMA LIMITED (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11807609-B2 | Deuterated compounds as immunomodulators | C3AR1, C5AR1, C5AR2 | IDO1 127/4885NR1H2 328/4885GAA 4867/4885 |
| US-20220389017-A1 | NOVEL PURINE DERIVATIVE, INTERMEDIATE AND APPLICATION THEREOF IN PREPARING ANTICANCER MEDICINE | PNP, ENTPD5, NTPCR | IDO1 1266/4885NR1H2 3412/4885GAA 1212/4885 |
| US-20120046467-A1 | QUATERNARY AMMONIUM SALT COMPOUNDS | ADRB2, AGTR2, ADRB3 | IDO1 3275/4885NR1H2 191/4885GAA 3030/4885 |
| US-20190144389-A1 | DEUTERATED COMPOUNDS AS IMMUNOMODULATORS | C3AR1, C5AR1, C5AR2 | IDO1 127/4885NR1H2 328/4885GAA 4867/4885 |
| US-11999698-B2 | Fused piperidinyl bicyclic and related compounds as modulators of C5a receptor | C5AR1, C5AR2, C3AR1 | IDO1 1926/4885NR1H2 2280/4885GAA 4755/4885 |
| US-20200290969-A1 | FUSED PIPERIDINYL BICYCLIC AND RELATED COMPOUNDS AS MODULATORS OF C5A RECEPTOR | C5AR1, C5AR2, C3AR1 | IDO1 1926/4885NR1H2 2280/4885GAA 4755/4885 |
| US-20210276955-A1 | DEUTERATED COMPOUNDS AS IMMUNOMODULATORS | C3AR1, C5AR1, C5AR2 | IDO1 127/4885NR1H2 328/4885GAA 4867/4885 |
| US-12054488-B2 | Pyrazolopyrimidine compound and preparation method therefor and use thereof in preparation of anti-cancer drug | PIK3CA, PIK3CD, PIK3R5 | IDO1 4123/4885NR1H2 3148/4885GAA 2458/4885 |
| US-11149009-B2 | Fused piperidinyl bicyclic and related compounds as modulators of C5A receptor | C5AR1, C5AR2, C3AR1 | IDO1 1926/4885NR1H2 2280/4885GAA 4755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.