Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.36 |
| ▸ | PPARG | P37231 | 6/20 | 0.36 |
| ▸ | RARG | P13631 | 4/20 | 0.36 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5668493 | 0.89 | ALOX5 (0.39) | — | |
| SCHEMBL5668478 | 0.87 | RARG (0.39) | RXRAPPARGRARGTNFRSF1A | |
| SCHEMBL5663415 | 0.85 | RXRA (0.38) | RXRAPPARGRARGTNFRSF1A | |
| SCHEMBL5667374 | 0.85 | RXRA (0.38) | RXRAPPARGRARGTNFRSF1A | |
| SCHEMBL6685293 | 0.81 | HMGCR (0.41) | RXRA | |
| SCHEMBL5662810 | 0.79 | RXRA (0.38) | RXRAPPARGRARGTNFRSF1A | |
| SCHEMBL6680912 | 0.78 | RXRA (0.41) | RXRAPPARGRARGTNFRSF1A | |
| SCHEMBL5662542 | 0.78 | RXRA (0.41) | RXRAPPARGRARGTNFRSF1A | |
| SCHEMBL6683401 | 0.77 | RXRA (0.35) | RXRAPPARGRARGTNFRSF1A | |
| SCHEMBL5667943 | 0.77 | ALOX5 (0.41) | RXRAPPARGRARGTNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026242-A2 | SUBSTITUTED KETOPHOSPHONATE INHIBITORS OF TUMOR CELL PROLIFERATION | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | claimed |
| WO-2004026242-A2 | SUBSTITUTED KETOPHOSPHONATE INHIBITORS OF TUMOR CELL PROLIFERATION | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | disclosed |