Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680296 | 0.86 | HDAC1 (0.72) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL23392538 | 0.86 | HDAC1 (0.72) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL6685576 | 0.82 | ALDH1A1 (0.59) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL6688392 | 0.82 | KMT2A (0.65) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL28552640 | 0.82 | MEN1 (0.68) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL23392572 | 0.81 | PTGS1 (0.76) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL6691310 | 0.81 | PTGS1 (0.76) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL23392575 | 0.81 | HDAC1 (0.75) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL6689596 | 0.81 | HDAC1 (0.66) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL6685305 | 0.80 | MEN1 (0.60) | MEN1KMT2AKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |