Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680293 | 0.86 | L3MBTL1 (0.71) | ALDH1A1KDM4ENPSR1L3MBTL1ATM | |
| SCHEMBL6685582 | 0.82 | MEN1 (0.55) | ALDH1A1KDM4EHTTNPSR1USP2 | |
| SCHEMBL6688390 | 0.82 | L3MBTL1 (0.62) | ALDH1A1KDM4EHTTNPSR1HSD17B10 | |
| SCHEMBL6691306 | 0.82 | AURKA (0.66) | ALDH1A1L3MBTL1ATMMEN1KMT2A | |
| SCHEMBL6689594 | 0.81 | L3MBTL1 (0.64) | ALDH1A1KDM4ENPSR1L3MBTL1ATM | |
| SCHEMBL6685302 | 0.80 | L3MBTL1 (0.57) | ALDH1A1KDM4ENPSR1USP2L3MBTL1 | |
| SCHEMBL6689714 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KDM4EHTTNPSR1USP2 | |
| SCHEMBL6689634 | 0.80 | MAPK1 (0.63) | ALDH1A1KDM4EHTTNPSR1L3MBTL1 | |
| SCHEMBL6687800 | 0.80 | LMNA (0.59) | ALDH1A1KDM4ENPSR1POLBL3MBTL1 | |
| SCHEMBL6682324 | 0.78 | UBE2I (0.59) | ALDH1A1KDM4EHTTNPSR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |