Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | UNG | P13051 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.33 |
| ▸ | ABAT | P80404 | 3/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817781 | 0.78 | CA12 (0.37) | ALDH1A1HSD17B10TDP1PTGS2TYR | |
| SCHEMBL7819754 | 0.74 | KDM4E (0.44) | ALDH1A1KDM4ERAB9ACYP2A6HPGD | |
| SCHEMBL7818300 | 0.73 | KDM4E (0.47) | ALDH1A1HSD17B10TDP1KDM4EKMT2A | |
| SCHEMBL23775788 | 0.72 | ALDH1A1 (0.59) | ALDH1A1HSD17B10TDP1PTGS2KDM4E | |
| SCHEMBL7823486 | 0.72 | ALDH1A1 (0.49) | ALDH1A1HSD17B10KDM4EKMT2AHPGD | |
| SCHEMBL5337947 | 0.71 | POLB (0.44) | ALDH1A1HSD17B10TDP1KDM4ERAB9A | |
| SCHEMBL9260062 | 0.71 | CA12 (0.37) | ALDH1A1HSD17B10TDP1PTGS2TYR | |
| SCHEMBL6264002 | 0.71 | ALDH1A1 (0.37) | ALDH1A1HSD17B10TDP1KDM4ERAB9A | |
| SCHEMBL2798568 | 0.69 | ALDH1A1 (0.55) | ALDH1A1HSD17B10TDP1PTGS2KDM4E | |
| SCHEMBL6489263 | 0.67 | ALDH1A1 (0.53) | ALDH1A1HSD17B10TDP1PTGS2UNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004070045-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 6-FORMYL-1,4-BENZODIOXIN-2-CARBOXYLIC ACID DERIVATIVE | NISSHIN PHARMA INC. (JP) | 2004-08-19 | — | — | WO | disclosed |