Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818300 | 0.86 | KDM4E (0.47) | ALDH1A1KMT2AKDM4EMEN1HSD17B10 | |
| SCHEMBL8580159 | 0.83 | MAPT (0.39) | ALDH1A1KMT2AKDM4EMEN1TP53 | |
| SCHEMBL6332615 | 0.77 | KMT2A (0.62) | ALDH1A1KMT2AKDM4EMEN1TP53 | |
| SCHEMBL7817781 | 0.76 | CA12 (0.37) | ALDH1A1KMT2AMEN1CYP2C9HPGD | |
| SCHEMBL7819754 | 0.75 | KDM4E (0.44) | ALDH1A1KDM4EHPGD | |
| SCHEMBL5337947 | 0.72 | POLB (0.44) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL9255645 | 0.72 | CA12 (0.47) | ALDH1A1KDM4ETP53CYP2C9HPGD | |
| SCHEMBL6685590 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL6264002 | 0.72 | ALDH1A1 (0.37) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL4204148 | 0.71 | MTNR1A (0.42) | ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841337-B1 | Substituted 7,12-dioxabenzo(a)anthracene derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-09-05 | — | — | EP | disclosed |
| EP-0841337-A1 | Substituted 7,12-dioxabenzo(a)anthracene derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-13 | — | — | EP | disclosed |