Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 3/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23775788 | 0.93 | ALDH1A1 (0.59) | ALDH1A1HSD17B10TDP1AHRKIF11 | |
| SCHEMBL5571073 | 0.85 | SMN1; SMN2 (0.53) | ALDH1A1HSD17B10TDP1KDM4ERAB9A | |
| SCHEMBL7186528 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1AHRKIF11 | |
| SCHEMBL10512849 | 0.78 | AHR (0.48) | ALDH1A1TDP1AHRRAB9AALOX5 | |
| SCHEMBL30811568 | 0.77 | ALOX5 (0.59) | ALDH1A1HSD17B10TDP1KIF11RAB9A | |
| SCHEMBL28230706 | 0.77 | ALOX5 (0.64) | ALDH1A1HSD17B10TDP1KIF11RAB9A | |
| SCHEMBL27298809 | 0.77 | MAOA (0.59) | ALDH1A1HSD17B10TDP1KIF11CYP2A6 | |
| SCHEMBL18536089 | 0.77 | CYP2A6 (0.55) | ALDH1A1HSD17B10TDP1CYP2A6RAB9A | |
| SCHEMBL11557550 | 0.77 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TDP1AHRKIF11 | |
| SCHEMBL27344293 | 0.77 | ALOX5 (0.59) | ALDH1A1HSD17B10TDP1KIF11RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858732-B2 | Photochromic benzodioxine fused naphthopyran compounds, compositions and articles containing those naphthopyran compounds | VISION-EASE LENS, INC. (US) | 2005-02-22 | — | — | US | disclosed |
| WO-2003074528-A1 | PHOTOCHROMIC BENZODIOXINE - FUSED NAPHTHOPYRAN COMPOUNDS AND COMPOSITIONS AND ARTICLES CONTAINING THEM | VISION-EASE LENS, INC. (US) | 2003-09-12 | — | — | WO | disclosed |
| US-20030168645-A1 | Photochromic benzodioxine fused naphthopyran compounds, compositions and articles containing those naphthopyran compounds | VISION-EASE LENS, INC. | 2003-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030168645-A1 | Photochromic benzodioxine fused naphthopyran compounds, compositions and articles containing those naphthopyran compounds | NDC1, BRIX1, NR2E3 | ALDH1A1 1573/4885HSD17B10 2267/4885TDP1 3018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.