SCHEMBL668562

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9887764	0.81	ALDH1A1 (0.38)	GRIK1ALDH1A1MAPK1TSHRSRD5A2
	SCHEMBL668220	0.81	MAPK1 (0.38)	GRIK1ALDH1A1MAPK1KMT2ASRD5A2
	SCHEMBL29973872	0.77	CYP2C9 (0.40)	ALDH1A1MAPK1TSHRSMN1; SMN2KDM4E
	SCHEMBL30949546	0.77	TSHR (0.39)	ALDH1A1TSHRSMN1; SMN2RAB9AKDM4E
	SCHEMBL3242216	0.75	ALDH1A1 (0.44)	GRIK1ALDH1A1MAPK1TSHRKMT2A
	SCHEMBL668357	0.73	ALOX15 (0.34)	ALDH1A1MAPK1KMT2ASMN1; SMN2RAB9A
	SCHEMBL21829025	0.71	ALDH1A1 (0.41)	ALDH1A1MAPK1KMT2ASRD5A2SMN1; SMN2
	SCHEMBL9887767	0.68	ALDH1A1 (0.37)	GRIK1ALDH1A1MAPK1TSHRKMT2A
	SCHEMBL217628	0.67	TSHR (0.61)	ALDH1A1TSHRKMT2ASMN1; SMN2KDM4E
	SCHEMBL32690872	0.67	TSHR (0.61)	ALDH1A1TSHRKMT2ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.