⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17508779 | 0.84 | — | — | |
| SCHEMBL12705 | 0.83 | — | — | |
| SCHEMBL1787237 | 0.83 | L3MBTL1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL3957127 | 0.81 | HTR1A (0.33) | — | |
| SCHEMBL23791571 | 0.77 | — | — | |
| SCHEMBL10115565 | 0.77 | NPC1 (0.43) | — | |
| SCHEMBL2042551 | 0.77 | — | — | |
| SCHEMBL2572706 | 0.77 | CHRM2 (0.38) | — | |
| Hydrochloric Acid SCHEMBL20588397 | 0.75 | CHRM2 (0.37) | — | |
| SCHEMBL13189060 | 0.74 | L3MBTL1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563717-B | Piperidine CXCR7 receptor modulators | 爱杜西亚药品有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-109563085-B | Piperidine CXCR7 receptor modulators | 爱杜西亚药品有限公司 | 2022-08-09 | — | — | CN | disclosed |
| EP-3490986-B1 | PIPERIDINE CXCR7 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-11-24 | — | — | EP | disclosed |
| EP-3798217-A1 | PIPERIDINE CXCR7 RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2021-03-31 | — | — | EP | disclosed |
| US-20200385373-A1 | PIPERIDINE CXCR7 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2020-12-10 | — | — | US | disclosed |
| US-10752620-B2 | Piperdine CXCR7 receptor modulators | IDORSIA PHARMACEUTICALS LTD. (CH) | 2020-08-25 | — | — | US | disclosed |
| CN-110563717-A | piperidine CXCR7receptor modulators | 爱杜西亚药品有限公司 | 2019-12-13 | — | — | CN | disclosed |
| US-20190169180-A1 | PIPERDINE CXCR7 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD. (CH) | 2019-06-06 | — | — | US | disclosed |
| EP-3490986-A1 | PIPERIDINE CXCR7 RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2019-06-05 | — | — | EP | disclosed |
| CN-109563085-A | piperidine CXCR7 receptor modulators | 爱杜西亚药品有限公司 | 2019-04-02 | — | — | CN | disclosed |
| EP-0282502-B1 | IMIDAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-05-15 | — | — | EP | disclosed |
| US-4987146-A | N-hetaryl imidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-22 | — | — | US | disclosed |
| US-4960777-A | Anxiolytic agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| US-4952698-A | Imidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-08-28 | — | — | US | disclosed |
| EP-0358595-A1 | N-hetaryl imidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-03-14 | — | — | EP | disclosed |
| US-4877792-A | ANXIOLYTIC AGENTS; ANTICONVULSANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-10-31 | — | — | US | disclosed |
| EP-0323799-A1 | Imidazole derivatives II | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-07-12 | — | — | EP | disclosed |
| EP-0282502-A1 | IMIDAZOLE DERIVATIVES. | SCHERING AG (DE) | 1988-09-21 | — | — | EP | disclosed |
| WO-1988001268-A1 | IMIDAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1988-02-25 | — | — | WO | disclosed |
| EP-0237467-A2 | Heteroaryl-oxy-beta-carboline derivatives, their preparation and use as medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-09-16 | — | — | EP | disclosed |