Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680891 | 0.91 | PTGS1 (0.55) | PTGS1PTGS2L3MBTL1MALT1CYP1A2 | |
| SCHEMBL6681813 | 0.83 | PTGS1 (0.52) | PTGS1PTGS2L3MBTL1MALT1CYP1A2 | |
| SCHEMBL6684663 | 0.82 | PTGS1 (0.62) | PTGS1PTGS2L3MBTL1MALT1RAB9A | |
| SCHEMBL6685190 | 0.80 | PTGS1 (0.54) | PTGS1PTGS2L3MBTL1MALT1RAB9A | |
| SCHEMBL6686621 | 0.80 | PTGS1 (0.54) | PTGS1PTGS2L3MBTL1MALT1MDM2 | |
| SCHEMBL6681657 | 0.80 | PTGS1 (0.52) | PTGS1PTGS2L3MBTL1CYP1A2MDM2 | |
| SCHEMBL6686314 | 0.78 | L3MBTL1 (0.59) | PTGS2L3MBTL1MDM2BCL2MCL1 | |
| SCHEMBL6687111 | 0.78 | PTGS1 (0.52) | PTGS1PTGS2L3MBTL1MALT1MDM2 | |
| SCHEMBL6690184 | 0.77 | L3MBTL1 (0.57) | PTGS1PTGS2L3MBTL1MDM2BCL2 | |
| SCHEMBL6683341 | 0.77 | PTGS1 (0.58) | PTGS1PTGS2L3MBTL1MDM2BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |