Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686978 | 0.90 | MEN1 (0.46) | L3MBTL1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6686314 | 0.84 | L3MBTL1 (0.59) | L3MBTL1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6682894 | 0.83 | ALDH1A1 (0.62) | L3MBTL1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6681813 | 0.81 | PTGS1 (0.52) | L3MBTL1HPGDPTGS2MDM2BCL2 | |
| SCHEMBL6681657 | 0.80 | PTGS1 (0.52) | L3MBTL1MAPTALDH1A1PTGS2MDM2 | |
| SCHEMBL6685965 | 0.77 | PTGS1 (0.53) | L3MBTL1PTGS2MDM2BCL2MCL1 | |
| SCHEMBL6683341 | 0.77 | PTGS1 (0.58) | L3MBTL1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6685914 | 0.76 | L3MBTL1 (0.41) | L3MBTL1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6684498 | 0.75 | KMT2A (0.48) | L3MBTL1MAPTALDH1A1HPGDMDM2 | |
| SCHEMBL6684522 | 0.75 | MEN1 (0.48) | L3MBTL1MAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |