SCHEMBL668599

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL668052	0.84	LMNA (0.49)	LMNASTAT3RAB9ANPC1SMN1; SMN2
	SCHEMBL668685	0.83	MAPT (0.45)	LMNALIG1RAB9ANPC1SMN1; SMN2
	SCHEMBL668914	0.81	LMNA (0.46)	LMNASTAT3RAB9ANPC1SMN1; SMN2
	SCHEMBL10139047	0.81	SMN1; SMN2 (0.43)	LMNALIG1RAB9ANPC1SMN1; SMN2
	SCHEMBL668137	0.81	HTT (0.44)	LIG1RAB9ANPC1SMN1; SMN2KDM4E
	SCHEMBL10139038	0.79	CYP3A4 (0.55)	LIG1RAB9ANPC1SMN1; SMN2KDM4E
	SCHEMBL670845	0.78	KDM4E (0.32)	LMNASMN1; SMN2KDM4EPOLBGAA
	SCHEMBL17424946	0.78	KDM4E (0.41)	LMNALIG1STAT3RAB9ANPC1
	SCHEMBL668020	0.76	ABCB1 (0.66)	—
	SCHEMBL14703579	0.75	CYP3A4 (0.38)	LMNALIG1RAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.