SCHEMBL668685

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10139038	0.91	CYP3A4 (0.55)	TSHRHSD17B10KDM4ESMN1; SMN2KMT2A
	SCHEMBL10139047	0.88	SMN1; SMN2 (0.43)	MAPTGAATSHRMAPK1HSD17B10
	SCHEMBL668137	0.88	HTT (0.44)	GAATSHRHSD17B10KDM4ESMN1; SMN2
	SCHEMBL14703579	0.86	CYP3A4 (0.38)	MAPTGAATSHRMAPK1HSD17B10
	SCHEMBL667972	0.85	RAB9A (0.38)	MAPTGAAKDM4ESMN1; SMN2KMT2A
	SCHEMBL17424946	0.84	KDM4E (0.41)	KDM4ESMN1; SMN2KMT2AHTTMEN1
	SCHEMBL2422146	0.83	KDM4E (0.48)	MAPTGAATSHRMAPK1HSD17B10
	SCHEMBL668599	0.83	LMNA (0.40)	GAAKDM4ESMN1; SMN2KMT2AHTT
	SCHEMBL669102	0.81	GAA (0.53)	MAPTGAATSHRMAPK1HSD17B10
	SCHEMBL28299986	0.78	KDM4E (0.56)	MAPTGAATSHRMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.