Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.43 |
| ▸ | KDM6B | O15054 | 2/20 | 0.42 |
| ▸ | KDM5C | P41229 | 2/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335970 | 0.83 | LMNA (0.60) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| SCHEMBL11545391 | 0.77 | ALDH1A1 (0.30) | ALDH1A1 | |
| Succinic Acid SCHEMBL1921951 | 0.73 | EGLN1 (0.75) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL2148509 | 0.73 | EGLN1 (0.75) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL35204 | 0.73 | EGLN1 (0.75) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL16415716 | 0.73 | EGLN1 (0.75) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL17975779 | 0.73 | EGLN1 (0.75) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| SCHEMBL28409672 | 0.72 | — | — | |
| Succinic Acid SCHEMBL2305765 | 0.70 | EGLN1 (0.69) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL10776609 | 0.70 | EGLN1 (0.69) | LMNASLC15A2EGLN1ALKBH5SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162502-A | Immunotoxins | SANOFI (FR) | 1992-11-10 | — | — | US | disclosed |
| US-5037960-A | Antitumor agents | SANOFI (FR) | 1991-08-06 | — | — | US | disclosed |
| US-4954638-A | ANTIALLERGENS, ANTIINFLAMMATORY | MERCK FROSST CANADA, INC. (CA) | 1990-09-04 | — | — | US | disclosed |
| US-4767745-A | 1,5-DIFLUORO-2,4-DINITRO BENZENE AND 6-N-MALEIMIDOHEXANOIC ACID CHLORIDE AS COUPLING AGENTS; ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA, INC. (CA) | 1988-08-30 | — | — | US | disclosed |
| EP-0179959-A1 | Conjugates of leukotrienes with proteins | MERCK FROSST CANADA INC. (CA) | 1986-05-07 | — | — | EP | disclosed |
| US-4172207-A | Process for mercaptoalkanedicarboxylic acid esters | MACK GERRY P | 1979-10-23 | — | — | US | disclosed |