Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681568 | 0.86 | LTA4H (0.71) | LTA4HHRH3DRD3NPC1RAB9A | |
| SCHEMBL13472664 | 0.81 | LTA4H (0.61) | LTA4HHRH3DRD3NPC1RAB9A | |
| SCHEMBL14012816 | 0.81 | KDR (0.75) | LTA4HDRD3 | |
| SCHEMBL17842304 | 0.80 | NPC1 (0.70) | LTA4HHRH3NPC1RAB9AKCNH2 | |
| SCHEMBL17842350 | 0.79 | NPC1 (0.68) | LTA4HHRH3NPC1RAB9AKCNH2 | |
| SCHEMBL17842398 | 0.77 | LTA4H (0.54) | LTA4H | |
| SCHEMBL5175706 | 0.77 | LTA4H (0.68) | LTA4HNPC1RAB9AKCNH2 | |
| SCHEMBL7367813 | 0.77 | HRH3 (0.72) | LTA4HHRH3 | |
| SCHEMBL7139740 | 0.76 | LTA4H (1.00) | LTA4H | |
| SCHEMBL6041201 | 0.76 | POLB (0.63) | LTA4HNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058259-A1 | COMPOUND LIBRARIES OF N-(AMINOCARBONYL)-PIPERIDINE-4-CARBOXAMIDE DERIVATIVES CAPABLE OF BINDING TO G-PROTEIN COUPLED RECEPTORS | BIOFOCUS PLC (GB) | 2004-07-15 | — | — | WO | disclosed |