Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.72 |
| ▸ | LTA4H | P09960 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | GALR3 | O60755 | 1/20 | 0.60 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13472664 | 0.82 | LTA4H (0.61) | HRH3LTA4HMAPTGALR3 | |
| SCHEMBL6681568 | 0.82 | LTA4H (0.71) | HRH3LTA4H | |
| SCHEMBL493434 | 0.81 | MEN1 (0.61) | MAPT | |
| SCHEMBL3580727 | 0.81 | HRH3 (1.00) | HRH3LTA4HACHERAD52 | |
| SCHEMBL30777699 | 0.81 | HRH3 (1.00) | HRH3LTA4HACHERAD52 | |
| SCHEMBL7459048 | 0.81 | MMP1 (0.59) | HRH3MAPTGALR3 | |
| SCHEMBL3571208 | 0.81 | HRH3 (1.00) | HRH3ACHERAD52 | |
| SCHEMBL7463601 | 0.79 | MMP1 (0.59) | HRH3ACHEMAPTGALR3 | |
| SCHEMBL5175706 | 0.77 | LTA4H (0.68) | LTA4H | |
| SCHEMBL16795357 | 0.77 | HRH3 (0.74) | HRH3LTA4HACHERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099035-A1 | Method for preparing alpha-sulfonyl hydroxamic acid derivatives | WYETH HOLDINGS CORPORATION | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099035-A1 | Method for preparing alpha-sulfonyl hydroxamic acid derivatives | MMP25, ADAMTS5, MMP9 | HRH3 2528/4885LTA4H 103/4885ACHE 725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.