Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 18/20 | 0.46 |
| ▸ | CTSL | P07711 | 14/20 | 0.45 |
| ▸ | CTSK | P43235 | 10/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687608 | 0.87 | CTSS (0.50) | CTSSCTSLCTSK | |
| SCHEMBL6688774 | 0.85 | CTSS (0.46) | CTSSCTSLCTSK | |
| SCHEMBL6685630 | 0.85 | NPC1 (0.51) | CTSSCTSLCTSKTRPV1 | |
| SCHEMBL5843619 | 0.84 | CTSS (0.68) | CTSSCTSLCTSK | |
| SCHEMBL5842262 | 0.84 | CTSS (0.68) | CTSSCTSLCTSK | |
| SCHEMBL6690343 | 0.84 | CTSS (0.59) | CTSSCTSLCTSK | |
| SCHEMBL6686940 | 0.83 | CTSS (0.56) | CTSSCTSLCTSKTRPV1 | |
| SCHEMBL6689357 | 0.83 | CTSS (0.50) | CTSSCTSLCTSKTRPV1 | |
| SCHEMBL6690062 | 0.82 | CTSS (0.48) | CTSSCTSLCTSKTRPV1 | |
| SCHEMBL6686619 | 0.81 | CTSS (0.46) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |