Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.59 |
| ▸ | CTSL | P07711 | 12/20 | 0.59 |
| ▸ | CTSK | P43235 | 10/20 | 0.59 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694188 | 0.91 | CTSS (0.71) | CTSSCTSLCTSKMEN1KMT2A | |
| SCHEMBL6685630 | 0.86 | NPC1 (0.51) | CTSSCTSLCTSKRAB9AHPGD | |
| SCHEMBL6688774 | 0.85 | CTSS (0.46) | CTSSCTSLCTSK | |
| SCHEMBL6686273 | 0.84 | CTSS (0.46) | CTSSCTSLCTSK | |
| SCHEMBL5842109 | 0.84 | CTSS (0.84) | CTSSCTSLCTSK | |
| SCHEMBL5842104 | 0.84 | CTSS (0.84) | CTSSCTSLCTSK | |
| SCHEMBL6694172 | 0.84 | CTSS (0.47) | CTSSCTSLCTSKMCHR1 | |
| SCHEMBL6686940 | 0.83 | CTSS (0.56) | CTSSCTSLCTSK | |
| SCHEMBL6689357 | 0.83 | CTSS (0.50) | CTSSCTSLCTSKRAB9AHPGD | |
| SCHEMBL6690062 | 0.83 | CTSS (0.48) | CTSSCTSLCTSKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |