SCHEMBL6686362

SCHEMBL6686362

N=C(OONC(=O)S)N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TSHR P16473 2/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
LMNA P02545 1/20 0.41
REN P00797 1/20 0.40
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3078245 0.76 CYP2D6 (0.45) ALDH1A1TSHRLMNACYP1A2CYP2D6
SCHEMBL3072971 0.70 LMNA (0.57) KDM4EALDH1A1NPSR1TSHRLMNA
SCHEMBL23791771 0.70 ALDH1A1 (0.47) ALDH1A1NPSR1TSHRGRIN2DGRIN3B
SCHEMBL6869925 0.69 LMNA (0.55) KDM4EALDH1A1NPSR1TSHRLMNA
Selenium SCHEMBL11585003 0.69 LMNA (0.55) KDM4EALDH1A1NPSR1TSHRLMNA
SCHEMBL825414 0.68 LMNA (0.63) KDM4EALDH1A1NPSR1TSHRLMNA
SCHEMBL1273845 0.67 GRIN2D (0.81) KDM4EALDH1A1NPSR1GRIN2DGRIN3B
SCHEMBL5932157 0.67 LMNA (0.57) KDM4EALDH1A1NPSR1TSHRLMNA
Carbamic Acid SCHEMBL6466030 0.67 LMNA (0.57) KDM4EALDH1A1NPSR1TSHRGRIN2D
SCHEMBL1386526 0.67 LMNA (0.57) KDM4EALDH1A1NPSR1TSHRGRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 WO disclosed